皇家华人

皇家华人
皇家华人 Cancer Center

Biorepository and Tissue Analytics Shared Resource (BTASR)

The Biorepository and Tissue Analytics Shared Resource supports cancer research by providing MCW Cancer Center members with human tissues and other biospecimens, biospecimen processing services and expertise, and histopathology and advanced tumor analytics.

Scheduling, Location, and Hours of Operation

Biorepository: Dynacare Building, lower level
Tissue Analytics: Translational and Biomedical Research Center, 4th floor
Monday鈥揊riday from 8 a.m.-5 p.m.

Services and Technologies

BTASR provides a broad range of biospecimen services, including standard and custom processing, leading-edge digital pathology analytics, clinical trial support, and storage.

CLIA-compliant and accredited by the College of American Pathologists, BTASR ensures quality operation and access to meticulously collected and quality-controlled specimens, vetted protocols, standard operating procedures, and knowledgeable, highly-trained staff.

View the Tissue Bank Biorepository FY25 price sheet

View the Tissue Analytics FY25 Price Sheet price sheet

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Tumor Tissues and Biofluids
  • Frozen/fresh tumor tissue for PDX, ex vivo explants/organoids, cell lines
  • Viable bone marrow, blood, cord blood
Multiplex Quantitative IF-Histocytometry
  • Solid tumor immunoprofiling
  • Quantitative multiplex IF imaging
  • Tissue processor, microtomes, embedding stations, autostainer, and coverslipper
  • Agilent Dako Omnis; Leica Bond Rx
  • 3DHistech Pannoramic Flash (bright field and IF); Akoya PhenoImager (7-9 color IF scanner)
  • Software: Tissue Studio, Akoya inForm, QuPath
Nucleic Acid (RNA/DNA) Purification
  • Frozen tissue: QIAGEN column purification
  • FFPE tissue: Purigen Ionic isotachophoresis 
Storage Services
  • Data logging and barcoding of samples
  • Monitored cryostorage
Biorepository and Tissue Analytics Shared Resource

iLab Requests and Support

Access the links below to learn how to register for iLab and submit requests.

Leadership

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Steven Kroft, MD

Director, Biorepository and Tissue Analytics Shared Resource

View Profile

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Mary Rau

Research Program Director

mrau@mcw.edu

Notable Publications

 (Zenga J, Awan M, Frei A, Foeckler J, Kuehn R, Espinosa OV, Bruening J, Massey B, Wong S, Shreenivas A, Shukla M, Kasprzak J, Sun Y, Shaheduzzaman M, Chen F, Kearl T, Himburg HA) Transl Oncol 2024 Jun;44:101927 PMID: 38641374; DOI: 10.1016/j.tranon.2024.101927; Scopus ID: 2-s2.0-85187349354

(Shrestha H, Rädler PD, Dennaoui R, Wicker MN, Rajbhandari N, Sun Y, Peck AR, Vistisen K, Triplett AA, Beydoun R, Sterneck E, Saur D, Rui H, Wagner KU) Cell Rep 2024 May 28;43(5):114202 PMID: 38733583; PMCID: PMC11194014; DOI: 10.1016/j.celrep.2024.114202; Scopus ID: 2-s2.0-85192447874

 (Buradagunta CS, Arsang-Jang S, Massat B, Thapa B, Patek V, D'Souza A, Auer P, Urrutia R, Janz S, Dhakal B, Hari P, Dong J) Leukemia 2024 Feb;38(2):383-385 PMID: 37919604; DOI: 10.1038/s41375-023-02078-6; Scopus ID: 2-s2.0-85175540732

 (Kameyama H, Dondapati P, Simmons R, Leslie M, Langenheim JF, Sun Y, Yi M, Rottschaefer A, Pathak R, Nuguri S, Fung KM, Tsaih SW, Chervoneva I, Rui H, Tanaka T) Cell Rep Med 2023 Dec 19;4(12):101330 PMID: 38118415; PMCID: PMC10772461; DOI: 10.1016/j.xcrm.2023.101330; Scopus ID: 2-s2.0-85180077828

(Chaudhary LN, Jorns JM, Sun Y, Cheng YC, Kamaraju S, Burfeind J, Gonyo MB, Kong AL, Patten C, Yen T, Cortina CS, Carson E, Johnson N, Bergom C, Tsaih SW, Banerjee A, Wang Y, Chervoneva I, Weil E, Chitambar CR, Rui H) Breast Cancer Res Treat 2023 Oct;201(3):387-396 PMID: 37460683; PMCID: PMC10795510; DOI: 10.1007/s10549-023-07038-3; Scopus ID: 2-s2.0-85164922339

(Chervoneva I, Peck AR, Sun Y, Yi M, Udhane SS, Langenheim JF, Girondo MA, Jorns JM, Chaudhary LN, Kamaraju S, Bergom C, Flister MJ, Hooke JA, Kovatich AJ, Shriver CD, Hu H, Palazzo JP, Bibbo M, Hyslop T, Nevalainen MT, Pestell RG, Fuchs SY, Mitchell EP, Rui H) JCO Precis Oncol 2023 Jan;7:e2100498 PMID: 36652667: PMCID: PMC9928763; DOI: 10.1200/PO.21.00498

(Sun Y, Yang N, Utama FE, Udhane SS, Zhang J, Peck AR, Yanac A, Duffey K, Langenheim JF, Udhane V, Xia G, Peterson JF, Jorns JM, Nevalainen MT, Rouet R, Schofield P, Christ D, Ormandy CJ, Rosenberg AL, Chervoneva I, Tsaih SW, Flister MJ, Fuchs SY, Wagner KU, Rui H) Sci Adv 2021 Sep 17;7(38):eabc8145 PMID: 34524841; PMCID: PMC8443188; DOI: 10.1126/sciadv.abc8145; Scopus ID: 2-s2.0-85115168052