Milwaukee ROC TXA Trial

Pre-hospital Tranexamic Acid (TXA)

TXA Medics

What is the purpose of the TXA Study?
To determine if Tranexamic Acid (TXA) given in the prehospital setting improves the long-term neurologic outcome compared to placebo in patients with moderate to severe traumatic brain injury (TBI). TBI is the leading cause of death and disability due to trauma and is the number one cause of death in people younger than 40 years old.
For more information on the TXA study, please view this Power Point slide presentation (PDF).

How is the TXA study being conducted in Milwaukee?
This research is being conducted by the 皇家华人’s Resuscitation Research Center in partnership with the and . The paramedics of MCEMS will enroll patients who have a traumatic brain injury, meet the TXA eligibility criteria, and who are not wearing an opt-out bracelet or necklace. Since these patients will not be able to provide informed consent because they are unconscious and require immediate treatment, this study is being conducted under the Exception from Informed Consent guidelines by the Food and Drug Administration.

View more information about Exception From Informed Consent Research

If you would like to opt-out of the TXA study, view the Opt-Out information page to find out how.

Public Notices
TXA Intermediate Public Announcement (PDF)
TXA Risk Benefit Public Announcement (PDF)

Contact Us

RRC@mcw.edu | (414) 805-6493

FDA Requirements for Research Conducted Under Emergency Circumstances
Opt-Out
Cardiac Arrest FAQs (PDF)
Common Myths About Cardiac Arrest (PDF)

Non-Discrimination Statement
The 皇家华人 (MCW) is committed to fostering a diverse community of outstanding faculty, staff, and students, as well as ensuring equal educational opportunity, employment, and access to services, programs, and activities, without regard to an individual's race, color, national origin, religion, age, disability, sex, gender identity/expression, sexual orientation, marital status, pregnancy, predisposing genetic characteristic, or military status. Employees, students, applicants or other members of the MCW community (including but not limited to vendors, visitors, and guests) may not be subjected to harassment that is prohibited by law or treated adversely or retaliated against based upon a protected characteristic. MCW’s policy as well as federal and state laws and regulations prohibit unlawful discrimination and harassment.