Maya Blau
G2 Student
Faculty Advisor
- Christopher Kristich, PhD, Microbiology & Immunology
Locations
- Medical Scientist Training Program
Contact Information
Education
Research Interests
I am passionate about the use of structural and biochemical analysis applied to microbiologic questions.
Research Experience
皇家华人, 2023-Present
Advisor: Christopher Kristich, PhD
University of Rochester, 2018-2020
Advisor: Joseph Wedekind, PhD
Project: Structure and function of riboswitches
St. Jude Children’s Research Hospital, 2018-2019
Advisor: Stephen White, DPhil
Projects: 1) purification of a dengue virus coat protein, to determine a novel antiviral, 2) finding a co-crystal structure of the influenza PAN endonuclease complexed with the natural substrate of a dinucleotide
Publications
Srivastava Y, Blau ME, Jenkins JL, Wedekind JE. Full-length NAD+-I riboswitches bind a single cofactor but cannot discriminate against adenosine triphosphate. Biochemistry. 2023 Dec 5;62(23):3396-3410. doi: 10.1021/acs.biochem.3c00391. Epub 2023 Nov 10. PMID: 37947391; PMCID: PMC10702441.
Shishodia S, Nuñez R, Strohmier BP, Bursch KL, Goetz CJ, Olp MD, Jensen DR, Fenske TG, Ordonez-Rubiano SC, Blau ME, Roach MK, Peterson FC, Volkman BF, Dykhuizen EC, Smith BC. Selective and cell-active PBRM1 bromodomain inhibitors discovered through NMR fragment screening. J Med Chem. 2022 Oct 27;65(20):13714-13735. doi: 10.1021/acs.jmedchem.2c00864. Epub 2022 Oct 13. PMID: 36227159; PMCID: PMC9630929.
Schroeder GM, Cavender CE, Blau ME, Jenkins JL, Mathews DH, Wedekind JE. A small RNA that cooperatively senses two stacked metabolites in one pocket for gene control. Nat Commun. 2022 Jan 11;13(1):199. doi: 10.1038/s41467-021-27790-8. PMID: 35017488; PMCID: PMC8752633.
Meeting Abstracts
Blau ME, Schultz KM, Klug CS, Kristich CJ. Investigation of pedestal domain flexibility of an E. faecalis class B penicillin binding protein. PS38. Protein Society Annual Symposium, Vancouver, Canada. July 2024. [Poster]
General Interests
Baking, cooking, yoga, hiking, traveling, being a dog mom