Joseph Hennessey

皇家华人

Medical Scientist Training Program

Phase 1 Second Year Student

Locations

Medical Scientist Training Program

Contact Information

jhennessey@mcw.edu

Education

BS, Biomedical Sciences and Philosophy, Marquette University, 2022

Research Interests

Applying the tools of systems neuroscience, neurobiology, and pharmacology to gain insights into mechanisms of neural plasticity and the mechanisms by which novel plasticity-inducing therapeutics can be used to treat stress-linked psychiatric diseases.

Research Experience

皇家华人, 2022-2023
Advisor: John McCorvy
Project: Characterization of biased agonism of psychedelics at aminergic GPCRs

Marquette University, 2021-2022
Advisor: Alex Savtchouk, PhD
Project: Anatomical tracing of cerebello-thalamo-cortical circuitry

Marquette University, 2019-2020
Advisor: John Mantsch, PhD
Project: Neuropsychopharmacology of stress contributions to cocaine seeking

Publications

Wallach J, Cao AB, Calkins MM, Heim AJ, Lanham JK, Bonniwell EM, Hennessey JJ, Bock HA, Anderson EI, Sherwood AM, Morris H, de Klein R, Klein AK, Cuccurazzu B, Gamrat J, Fannana T, Zauhar R, Halberstadt AL, McCorvy JD. Identification of 5-HT2A receptor signaling pathways associated with psychedelic potential. Nat Commun. 2023 Dec 15;14(1):8221. doi: 10.1038/s41467-023-44016-1. PMID: 38102107; PMCID: PMC10724237.

Vargas MV, Dunlap LE, Dong C, Carter SJ, Tombari RJ, Jami SA, Cameron LP, Patel SD, Hennessey JJ, Saeger HN, McCorvy JD, Gray JA, Tian L, Olson DE. Psychedelics promote neuroplasticity through the activation of intracellular 5-HT2A receptors. Science. 2023 Feb 17;379(6633):700-706. doi: 10.1126/science.adf0435. Epub 2023 Feb 16. PMID: 36795823; PMCID: PMC10108900.

General Interests

Brazilian jiu-jitsu, meditation, environmentalism, hiking, soccer, philosophy, and cooking

Non-Discrimination Statement
The 皇家华人 (MCW) is committed to fostering a diverse community of outstanding faculty, staff, and students, as well as ensuring equal educational opportunity, employment, and access to services, programs, and activities, without regard to an individual's race, color, national origin, religion, age, disability, sex, gender identity/expression, sexual orientation, marital status, pregnancy, predisposing genetic characteristic, or military status. Employees, students, applicants or other members of the MCW community (including but not limited to vendors, visitors, and guests) may not be subjected to harassment that is prohibited by law or treated adversely or retaliated against based upon a protected characteristic. MCW’s policy as well as federal and state laws and regulations prohibit unlawful discrimination and harassment.