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Cell Biology, Neurobiology and Anatomy (CBNA)
Kazuhiro Aoki, PhD

Kazuhiro Aoki, PhD

Associate Professor; Technical Director, Translational Metabolomics Shared Resource, MCW Cancer Center

Locations

  • Cell Biology, Neurobiology & Anatomy
    BSB, 376D

Contact Information

Education

PhD, Kyoto University, Kyoto, Japan, 2001
MS, Shiga University, Shiga, Japan, 2000
BS, Shiga University, Shiga, Japan, 1995

Biography

Dr. Aoki received his MS in Science Pedagogy from Shiga University, Japan in 2000, PhD in Life Science from Kyoto University, Japan in 2004. His PhD studies focused on the structure and function of complex glycans in non-human organisms, including insect, nematode, shell, plant and microbes. Prior to beginning graduate program, he worked as a research scientist at a biotechnology company. He has an extensive experience in pharmaceutical assessment, evaluating the drug metabolism in aspect of pharmacokinetic and pharmacodynamic studies in Phase I study. He moved to Athens, GA in 2004 and performed postdoctoral training at the Complex Carbohydrate Research Center at the University of Georgia. He was a faculty member at the University of Georgia from 2008 to 2022 until he joined MCW in 2022. He also served as an invited Professor in the Advanced Spectroscopy in Chemistry, Erasmus Mundus master’s course at the Lille University of Science and Technology, France in 2017.

Research Interests

His study focuses on the development of analytical methodologies and their application to the field of multi-Omics to understand the structure and function of biomolecules (protein, lipid, carbohydrate, etc.). Comprehensive mass spectrometry-based technologies are employed to study the impact of biological molecules in multiple organisms. Advanced linked-Omics techniques are applied to study the structural dynamics in a broad range of biological samples, including human and mouse embryonic stem cells, cancer biopsy tissues, model organisms (Drosophila, zebrafish, nematode, microbes) and human biofluids (plasma, serum, RBC, CSF, urine, saliva) in order to identify stage- and tissue- specific molecules associated with disease progression and cell differentiation.

Publications

  • (Bohnsack RN, Misra SK, Liu J, Ishihara-Aoki M, Pereckas M, Aoki K, Ren G, Sharp JS, Dahms NM.) Sci Rep. 2024 Nov 06;14(1):26875 PMID: 39505925 PMCID: PMC11541866 11/07/2024

  • (Luna S, Malard F, Pereckas M, Aoki M, Aoki K, Olivier-Van Stichelen S.) Glycobiology. 2024 Apr 10;34(4) PMID: 38253038 PMCID: PMC11005170 01/23/2024

  • (Dookwah M, Wagner SK, Ishihara M, Yu SH, Ulrichs H, Kulik MJ, Zeltner N, Dalton S, Strauss KA, Aoki K, Steet R, Tiemeyer M.) Hum Mol Genet. 2023 Dec 01;32(24):3323-3341 PMID: 37676252 PMCID: PMC10695682 09/07/2023

  • (Rosenbalm KE, Lee-Sundlov MM, Ashline DJ, Grozovsky R, Aoki K, Hanneman AJS, Hoffmeister KM.) Blood Adv. 2023 Aug 22;7(16):4278-4290 PMID: 36952551 PMCID: PMC10424148 03/24/2023

  • (Hollenhorst MA, Tiemeyer KH, Mahoney KE, Aoki K, Ishihara M, Lowery SC, Rangel-Angarita V, Bertozzi CR, Malaker SA.) J Thromb Haemost. 2023 Apr;21(4):995-1009 PMID: 36740532 PMCID: PMC10065957 SCOPUS ID: 2-s2.0-85150252223 02/06/2023

  • (Wu CM, Wheeler KM, Cárcamo-Oyarce G, Aoki K, McShane A, Datta SS, Mark Welch JL, Tiemeyer M, Griffen AL, Ribbeck K.) NPJ Biofilms Microbiomes. 2023 Mar 23;9(1):11 PMID: 36959210 PMCID: PMC10036478 SCOPUS ID: 2-s2.0-85150885000 03/25/2023

  • (Scott H, Novikov B, Ugur B, Allen B, Mertsalov I, Monagas-Valentin P, Koff M, Baas Robinson S, Aoki K, Veizaj R, Lefeber DJ, Tiemeyer M, Bellen H, Panin V.) Elife. 2023 Mar 22;12 PMID: 36946697 PMCID: PMC10110239 SCOPUS ID: 2-s2.0-85151561936 03/23/2023

  • (Rudy N, Aoki K, Ananth A, Holloway L, Skinner C, Hurst A, Tiemeyer M, Steet R.) JIMD Rep. 2023 Mar;64(2):138-145 PMID: 36873089 PMCID: PMC9981410 03/07/2023

  • (Wang BX, Takagi J, McShane A, Park JH, Aoki K, Griffin C, Teschler J, Kitts G, Minzer G, Tiemeyer M, Hevey R, Yildiz F, Ribbeck K.) EMBO J. 2023 Feb 01;42(3):e111562 PMID: 36504455 PMCID: PMC9890226 SCOPUS ID: 2-s2.0-85143780784 12/13/2022

  • (Wang BX, Takagi J, McShane A, Park JH, Aoki K, Griffin C, Teschler J, Kitts G, Minzer G, Tiemeyer M, Hevey R, Yildiz F, Ribbeck K.) EMBO Journal. 1 February 2023;42(3) SCOPUS ID: 2-s2.0-85143780784 02/01/2023

  • (Takagi J, Aoki K, Turner BS, Lamont S, Lehoux S, Kavanaugh N, Gulati M, Valle Arevalo A, Lawrence TJ, Kim CY, Bakshi B, Ishihara M, Nobile CJ, Cummings RD, Wozniak DJ, Tiemeyer M, Hevey R, Ribbeck K.) Nat Chem Biol. 2022 Jul;18(7):762-773 PMID: 35668191 PMCID: PMC7613833 SCOPUS ID: 2-s2.0-85131603189 06/07/2022

  • (Gonzalez-Gil A, Porell RN, Fernandes SM, Maenpaa E, Li TA, Li T, Wong PC, Aoki K, Tiemeyer M, Yu ZJ, Orsburn BC, Bumpus NN, Matthews RT, Schnaar RL.) J Biol Chem. 2022 Jun;298(6):101960 PMID: 35452678 PMCID: PMC9130525 SCOPUS ID: 2-s2.0-85130705298 04/23/2022

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