皇家华人

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Quinn Hogan, MD

Quinn Hogan, MD

Professor

Contact Information

Education

BS, Stanford University, Stanford, CA
MD, Harvard Medical School, Boston, MA
Residency, Anesthesiology, 皇家华人
Fellowship, Pain Management, 皇家华人

Research Experience

  • Pain
  • Rats

Research Interests

  • Somatosensory physiology
  • Pain mechanisms
  • Novel analgesic approaches

Publications

  • (Shin SM, Itson-Zoske B, Fan F, Xiao Y, Qiu C, Cummins TR, Hogan QH, Yu H.) J Clin Invest. 2024 May 09;134(13) PMID: 38722683 PMCID: PMC11213509 SCOPUS ID: 2-s2.0-85197962514 05/10/2024

  • (Waltz TB, Chao D, Prodoehl EK, Enders JD, Ehlers VL, Dharanikota BS, Dahms NM, Isaeva E, Hogan QH, Pan B, Stucky CL.) JCI Insight. 2024 Mar 07;9(8) PMID: 38646936 PMCID: PMC11141882 SCOPUS ID: 2-s2.0-85191335156 04/22/2024

  • (Tran H, Feng Y, Chao D, Liu QS, Hogan QH, Pan B.) Pain. 2024 Jan 01;165(1):102-114 PMID: 37463226 PMCID: PMC10787817 SCOPUS ID: 2-s2.0-85179842560 07/18/2023

  • (Waltz TB, Chao D, Prodoehl EK, Ehlers VL, Dharanikota BS, Dahms NM, Isaeva E, Hogan QH, Pan B, Stucky CL.) bioRxiv. 2023 May 28 PMID: 37292928 PMCID: PMC10245981 06/09/2023

  • (Shin SM, Itson-Zoske B, Fan F, Gani U, Rahman M, Hogan QH, Yu H.) Mol Pain. 2023;19:17448069231174315 PMID: 37247618 PMCID: PMC10240879 SCOPUS ID: 2-s2.0-85160467897 05/30/2023

  • (Shin SM, Lauzadis J, Itson-Zoske B, Cai Y, Fan F, Natarajan GK, Kwok WM, Puopolo M, Hogan QH, Yu H.) Pain. 2022 Dec 01;163(12):2466-2484 PMID: 35420557 PMCID: PMC9562599 SCOPUS ID: 2-s2.0-85134128027 04/15/2022

  • (Woyach V, Sherman K, Hillard CJ, Hopp FA, Hogan QH, Dean C.) Am J Physiol Regul Integr Comp Physiol. 2022 Nov 01;323(5):R749-R762 PMID: 36154489 PMCID: PMC9639763 SCOPUS ID: 2-s2.0-85141004185 09/27/2022

  • (Chao D, Tran H, Hogan QH, Pan B.) Osteoarthritis Cartilage. 2022 Nov;30(11):1468-1481 PMID: 36030058 PMCID: PMC9588581 SCOPUS ID: 2-s2.0-85137699296 08/28/2022

  • (Itson-Zoske B, Shin SM, Xu H, Qiu C, Fan F, Hogan QH, Yu H.) Arthritis Res Ther. 2022 Jul 16;24(1):168 PMID: 35842727 PMCID: PMC9287929 SCOPUS ID: 2-s2.0-85134262185 07/17/2022

  • (Roberts CJ, Hopp FA, Hogan QH, Dean C.) Neurobiol Pain. 2022;12:100104 PMID: 36531614 PMCID: PMC9755024 12/20/2022

  • (Saber M, Schwabe D, Park HJ, Tessmer J, Khan Z, Ding Y, Robinson M, Hogan QH, Pawela CP.) Neuromodulation. 2022 Jan;25(1):53-63 PMID: 35041588 01/19/2022

  • (Feng Y, Li K, Roth E, Chao D, Mecca CM, Hogan QH, Pawela C, Kwok WM, Camara AKS, Pan B.) Front Cell Neurosci. 2021;15:689334 PMID: 34447298 PMCID: PMC8383341 SCOPUS ID: 2-s2.0-85113358817 08/28/2021

My laboratory focuses on identifying disrupted function of sensory neurons following injury and exploring novel therapies for pain. We employ combined physiological approaches of patch-clamp electrophysiology for identification of membrane biophysics, single unit recordings by sharp electrode in intact ganglia in vitro and in vivo to evaluate neuronal function in the absence of dissociation, teased fiber recording, and microfluorometry to characterize the cytoplasmic Ca2+ signal that follows membrane activation. These approaches are ideally suited to explore the basic mechanisms of pain. My research has also emphasized the importance of valid behavioral testing as a necessary criterion for relevant pain study, as I am aware from my clinical work of the potential for divergence between animal models and human disease. I as well as other scientists investigating pain mechanisms have come to recognize that there is a major shortfall in translation of these discoveries into therapies. Therefore, my research also explores and develops novel approaches for taking advantage of the extensive backlog of mechanistic discoveries, including targeting the sensory neuron for molecular manipulations, stem cell therapy, and electrical stimulation as treatment modalities.